I introduce flow zoometry, a whole-animal equivalent of flow cytometry, designed for large-scale, individual-level, high-content screening of animals. This approach addresses the fundamental bottlenecks in animal research: high costs, labor-intensive processes, time inefficiency, susceptibility to human error, and limited statistical significance. Flow zoometry marks a paradigm shift in high-throughput screening, extending the progression from molecules to cells and now from cells to entire animals.